The seven-member barrel now injects its edema factor and lethal factor proteins through its central channel and into the cell's interior.
12.
The other Nature paper reveals the detailed, three-dimensional makeup of " lethal factor, " one of the toxin proteins that enters cells.
13.
Protective antigen starts the process by opening a hole in blood cells that lets in edema factor and the even deadlier lethal factor.
14.
Examples of enzymes that ilomastat inhibit include thermolysin, and anthrax lethal factor endopeptidase ( LF ) produced by the bacterium " Bacillus anthracis ".
15.
If edema factor helps an anthrax infection begin, by killing off the body's first line of defense, lethal factor administers the coup de grace.
16.
It punches through the cell wall to permit two other toxins _ known as edema factor and lethal factor _ to sneak in and wreak havoc.
17.
Edema factor, for example, can make the anthrax protein that attacks the body's immune system, called " lethal factor, " up to 100 times more potent.
18.
In the second study, researchers recorded how the lethal factor protein of the anthrax toxin, known as LF, wended its deadly way through the human cell.
19.
The screening system devised by Italian researchers has already identified two chemical compounds that inhibit the " lethal factor " protein that anthrax unleashes on the body's immune system.
20.
The spores are then picked up by scavenger cells ( macrophages ) in the lungs and are transported through small vessels ( lethal factor, edema factor, and protective antigen.
