| 11. | The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity.
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| 12. | These genes belong to the TTL ( tubulin tyrosine ligase ) family.
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| 13. | The single-strand viral DNA ends are ligated by host DNA ligase.
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| 14. | The insert and the destination vector are then mixed together with DNA ligase.
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| 15. | Finally, the processed coding ends are ligated together by DNA ligase IV.
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| 16. | DNA ligase would most likely have to be incorporated into such a machine.
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| 17. | The family of proteins is known to possess ubiquitin-protein ligase activity.
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| 18. | Then, Ku70 is ubiquitinated by c-Cbl, an E3 ubiquitin ligase.
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| 19. | The resultant gap is then filled in using DNA polymerase I and DNA ligase.
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| 20. | Mdm2 also acts as an E3 ubiquitin ligase, is capable of polyubiquitinating p53.
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