It appears to be implicated in immune response associated with natural killer ( NK ) and lymphokine-activated killer ( LAK ) cell cytotoxicity.
12.
This decision was taken during the Second International Lymphokine Workshop in Switzerland ( 27-31 May 1979 in Ermatingen,'near'Interlaken ).
13.
Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells.
14.
This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate a role in integrin signaling pathways.
15.
CIK cells respond to these lymphokines, particularly IL-2, by lysing tumor cells that were already known to be resistant to NK cell or LAK cell activity.
16.
Cel-Sci Corp . is testing a product called MultiKine, which, like LK-200, is described as a mixture of lymphokines and cytokines that stimulate immune responses.
17.
In 1969 Dudley Dumonde proposed the term " lymphokine " to describe proteins secreted from lymphocytes and later, proteins derived from macrophages and monocytes in culture were called " monokines ".
18.
Biological products produced by recombinant DNA ( rDNA ) technology in animal cell cultures include enzymes, synthetic hormones, immunobiologicals ( monoclonal antibodies, interleukins, lymphokines ), and anticancer agents.
19.
A "'macrophage-activating factor "'( MAF ) is a lymphokine or other receptor based signal that primes macrophages towards cytotoxicity to tumors, cytokine secretion, or clearance of pathogens.
20.
For example, chrysotile fibres have been shown to depress the in vitro proliferation of phytohemagglutinin-stimulated peripheral blood lymphocytes, suppress natural killer cell lysis and significantly reduce lymphokine-activated killer cell viability and recovery.
