| 11. | Schuch and colleagues reported that the enzyme, called PlyG lysin, kills anthrax bacteria in the laboratory.
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| 12. | More well known proteins in this family include saposin-C, NK-lysin, and amoebopore.
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| 13. | All other lysins are monomeric and comprise two C-terminal domain binds to the cell wall substrate.
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| 14. | Lysins exhibit species-specific binding to their egg receptor, possibly through differences in charged surface residues.
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| 15. | Though designed to pierce the wall from the inside, the lysin enzyme can also crumble it from outside.
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| 16. | The lysin would be tested for toxicity in people and could then be stockpiled for use in an attack.
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| 17. | Injected into the bloodstream, lysin could serve as a therapy even against anthrax strains made resistant to antibiotics.
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| 18. | This is typical in many staphylococcal lysins as well as the streptococcal PlyC holoenzyme, which contains two catalytic domains.
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| 19. | The prototypical holin is the lambda phage S protein, which assists the lambda phage R protein ( lysin ).
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| 20. | This allows the lysin to be a quick and sensitive detector for anthrax spores that might be used in an attack.
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