This process occurs through an oxidation, which regenerates the pyrrolinium cation and formation of an enolate anion, and an intramolecular Mannich reaction.
12.
The compound is formed by reaction of ethylene urea with a 37 % solution of formalin and hydrochloric acid in a sequence of Mannich reactions.
13.
Biosynthesis of monoterpenoid indole alkaloids begins with the Mannich reaction of tryptamine and secologanin; it yields strictosidine which is converted to 4, 21-dehydrogeissoschizine.
14.
Imines synthesized in this fashion have been shown to undergo a one-pot Mannich reaction with 1, 3-dicarbonyl compounds, such as protected imine.
15.
To obtain the primary thia-?-Ala-OMe intermediate, a sequence of condensation, Mannich reaction, and palladium-catalyzed decarboxylation steps were performed.
16.
Chloroiodomethane is used in cyclopropanation ( " Simmon-Smith reaction " ), Mannich reaction, aminomethylation, epoxidation, ring opening and addition to terminal alkenes.
17.
The two reactants ( imine and enamine ) line up for the Mannich reaction with Si facial attack of the imine by the Si-face of the enamine-aldehyde.
18.
A reverse Pictet-Spengler reaction cleaves the C2 C3 bond, while a subsequent Mannich reaction forms the C3 C7 bond, and a Michael addition forms the C2 C16 bond to provide dehydropreakuammicine.
19.
The aza-Cope / Mannich reaction shows high diastereoselectivity, generally in accordance the results of allyl and amine substituents are installed on a ring, and thus cis or trans to one another.
20.
"' Acrylophenone "'is an organic compound with the formula C 9 H 8 O . It is prepared using acetophenone, formaldehyde, and an amine hydrochloride in a Mannich reaction.
