| 11. | The equatorial or marginal zone, which compose the walls of the blastocoel differentiate primarily into mesodermal tissue.
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| 12. | The clusters of mesodermal cells signal back to the epidermis to form the appropriate structure for that position.
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| 13. | The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types.
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| 14. | A mesodermal defects affecting angiogenesis and associated with persistent of the embryonic vascular network might explain the vascular anomalies.
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| 15. | Thus they express the intermediate filament protein vimentin, a feature used as a marker to distinguish their mesodermal origin.
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| 16. | In mammalian development, the absence of fibronectin leads to defects in mesodermal, neural tube, and vascular development.
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| 17. | Similarly, the absence of a normal fibronectin matrix in developing amphibians causes defects in mesodermal patterning and inhibits gastrulation.
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| 18. | In other cell types and developmental stages, ?-catenin may promote differentiation, especially towards mesodermal cell lineages.
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| 19. | Details on how BMP4 prevents T from inducing mesodermal genes, and only activate PGC specification genes, remain unclear.
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| 20. | It reaches its maximum state of development at about this stage and contributes mesodermal type cells to the surrounding tissue.
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