The eponymous " Kobelt's tubules " are named after him, which are remnants of mesonephric ducts in the paroophoron.
12.
Testosterone, which is secreted and converts the mesonephric ducts into male accessory structures, such as epididymis, vas deferens and seminal vesicle.
13.
Alfred Jost observed that while testosterone was required for mesonephric duct development, the regression of the paramesonephric duct was due to another substance.
14.
In both the male and the female the mesonephric duct develops into the trigone of urinary bladder, a part of the bladder wall.
15.
Testosterone secretion by the interstitial cells of the testes then causes the growth and development of the mesonephric ducts into male secondary sex organs.
16.
The mesonephric duct connects the primitive kidney, the " mesonephros ", to the cloaca and serves as the anlage for certain male reproductive organs.
17.
On the medial side of the mesonephric duct, from the sixth cervical to the third lumbar segments, a series of tubules, the Wolffian tubules, develops.
18.
One end grows toward and finally opens into the mesonephric duct, the other dilates and is invaginated by a tuft of capillary bloodvessels to form a glomerulus.
19.
During the formation of the reproductive system, the paramesonephric ducts are formed just lateral to the mesonephric ducts in both female and male embryos 6 weeks after fertilization.
20.
Embryologically, the trigone of the bladder is derived from the caudal end of mesonephric ducts, which is of mesodermal origin ( the rest of the bladder is endodermal ).
