| 11. | He also had metastases in his immuno-therapy-based approaches.
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| 12. | Distant spread ( metastases ), significantly reduces the median survival rate.
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| 13. | Improvements in the treatment of brain metastases are clearly needed.
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| 14. | If so, the inhibitors might travel through the bloodstream, squelching metastases.
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| 15. | And in half, the metastases took eight or more years to occur.
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| 16. | He coined the term melanoma and described metastases of melanoma to the lungs.
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| 17. | Metastases to skin and lungs have a better prognosis.
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| 18. | Metastases to brain, bone and liver are associated with a worse prognosis.
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| 19. | However, metastases do occur and are usually fatal.
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| 20. | However, patients with resectable metastases have survived for several years following diagnosis.
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