| 11. | These metabolites are also found after oxidation with rat hepatic microsomes " in vitro ".
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| 12. | Like other formamidines amitraz inhibits the synthesis of prostaglandin E2 from arachidonic acid by bovine seminal vesicle microsomes.
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| 13. | Emodin was mutagenic in the Salmonella / microsome assay, but gave inconsistent results in gene mutation assays.
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| 14. | ALD3H2 is expressed in the human liver and has been found to localize the microsome fraction inside the cell.
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| 15. | RGPR-p117 is present in the plasma membranes, cytoplasm, mitochondria, microsomes and nucleus of the cells.
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| 16. | A portion of the atomic sulfur formed in this reaction covalently binds to macromolecules of the liver and lung microsomes.
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| 17. | No hydroxylated metabolites were identified after incubation with rat liver microsomes ( S9 ) or in rat urine following oral dosing.
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| 18. | It also tested positive in a " Salmonella " / mammalian microsome assay and was shown to be genotoxic.
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| 19. | The proposed metabolic pathways of aconitine in human liver microsomes and the CYPs involved to it are summarized in the table above.
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| 20. | The first and most important step of metabolism of chlorfenvinphos in humans is accomplished by the enzyme cytochrome P450 in liver microsomes.
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