Consistent with this strategy, mouse ES stem cells have a mutation frequency about 100-fold lower than that of isogenic mouse somatic cells.
12.
Laboratory studies have demonstrated that therapeutics capable of increasing the mutation frequency as little as 2-fold results in collapse of the viral population.
13.
The most common of these maladies is cholera, which only began killing Europeans millennia after the CF mutation frequency was already established in the population.
14.
The mutation frequency of CpG sites within CpG islands of gene promoters was compared to the mutation frequency of CpG sites in non-coding regions of genes.
15.
The mutation frequency of CpG sites within CpG islands of gene promoters was compared to the mutation frequency of CpG sites in non-coding regions of genes.
16.
Despite these claims, the World Health Organization states, " children conceived before or after their father's exposure showed no statistically significant differences in mutation frequencies ".
17.
This further showed that the mutation frequency improved to be 12 times that of X-rays, 36 times that of procarbazine and over 200 times that of spontaneous mutations.
18.
Deficient expression of multiple DNA repair genes is often found in cancers, and may contribute to the thousands of mutations usually found in cancers ( see Mutation frequencies in cancers ).
19.
Deficient expression of multiple DNA repair genes are often found in cancers, and may contribute to the thousands of mutations usually found in cancers ( see Mutation frequencies in cancers ).
20.
Bacterial resistance to Arenicin-3 is thus less likely to occur than resistance to other antibiotics as current antibiotics on the market report a spontaneous mutation frequency of 10-5.
