The determination of dermomyotome and myotome is regulated by a gene regulatory network that includes a member of the T-box family, tbx6, ripply1, and mesp-ba.
12.
Specifically, it is first seen in the dorsomedial portion of the dermomyotome, which develops into the epaxial myotome . it is instead directly activated by the transcription factor Pax3 in hypaxial cells.
