They include isoquinolines, benzylisoquinolines, protoberberines, aporphins, protopines, narcotine, aconitum the highly toxic delphinium poisons . " ( Hoffer, p . 74 ) ( the protopines would also be substituted amphetamines as well as substituted 3, 4-methylenedioxyphenethylamines, narcotine, aka noscapine, would also be a substituted PEA, substituted amphetamine and substituted 3, 4-methylenedioxyphenethylamine)
12.
In or shortly after 1851, the drugs which had been discovered and extracted from their plants of origin and refined into pure crystalline salts soluble in water included morphine ( 1804 or late 1803 ), codeine ( 1832 ), narcotine / noscapine ( 1803-1805 ? ), papaverine ( 1814 ), cocaine ( 1855 ), caffeine ( 1819 ), quinine ( 1820 ), atropine ( 1831 ), scopolamine ( aka hyoscine, aka laevo-duboisine ) ( 1833 ? ), hyoscyamine or laevo-atropine ( 1831 ), opium salts mixtures ( c . 1840s ), chloral derivatives ( 1831 et seq . ), ephedrine ( 1836 ? ), nicotine ( 1828 ), and many others of all types, psychoactive and not.
