| 11. | Distalless-5, PAX3 and PAX7 prevent the border region from becoming either neural plate or epidermis.
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| 12. | Another cadherin, E-cadherin, is expressed by ectodermal cells in the process of neural plate development.
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| 13. | N-cadherin is critical to holding neural plate cells together.
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| 14. | The heart derives from splanchnopleuric mesenchyme in the neural plate which forms the cardiogenic region.
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| 15. | The midline of the neural plate is referred to the median hinge point ( MHP ).
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| 16. | Now, as the ectoderm continues to elongate, the ectodermal cells of the neural plate fold inward.
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| 17. | The neural plate folds outwards during the third week of gestation to form the neural groove.
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| 18. | The dorsal neural tube is patterned by BMPs from the epidermal ectoderm flanking the neural plate.
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| 19. | This strip is called the neural plate, and is the origin of the entire nervous system.
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| 20. | The neural plate will fold to produce the neural tube which will develop into the brain.
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