Nitrate or "'nitrite "'( ingested ) under conditions that result in endogenous nitrosation has been classified as " " Probably carcinogenic to humans " " ( World Health Organization ( WHO ) of the United Nations.
12.
This process, known formally as " S "-nitrosation ( and referred to by many in the field as " S "-nitrosylation ), has been shown to reversibly inhibit NOS3 activity in vascular endothelial cells.
13.
Hemoglobin is a prominent example of a heme protein that may be modified by �NO by both pathways : �NO may attach directly to the heme in the nitrosylation reaction, and independently form S-nitrosothiols by S-nitrosation of the thiol moieties.
14.
Hemoglobin is a prominent example of a heme protein that may be modified by NO by both pathways : NO may attach directly to the heme in the nitrosylation reaction, and independently form S-nitrosothiols by S-nitrosation of the thiol moieties.