It is 5x more potent and 500 times more selective than the commonly used ?-opioid antagonist norbinaltorphimine.
12.
Pharmacological treatments for alcohol addiction include drugs like naltrexone ( opioid antagonist ), disulfiram, acamprosate, and topiramate.
13.
The opioid antagonist drug nalmefene has also been trialled quite successfully for the treatment of compulsive gambling.
14.
Furthermore, there have been case reports that support the use of these opioid antagonists to treat excoriation disorder.
15.
If the respiratory depression occurs from opioid overdose, usually an opioid antagonist, most likely naloxone, will be administered.
16.
The opioid antagonist activity of Nalbuphine is one-fourth as potent as nalorphine and 10 times that of pentazocine.
17.
"' Naloxegol "'( selective opioid antagonist developed by AstraZeneca, licensed from Nektar Therapeutics, for the treatment of opioid-induced constipation.
18.
Administration of a ?-opioid antagonist such as alvimopan immediately after surgery can help reduce the severity and duration of ileus.
19.
An additionitional implication of the aforementioned findings is that congenital insensitivity to pain may be clinically treatable with opioid antagonists.
20.
Both the inhibition and increase of dopamine release by GHB are inhibited by opioid antagonists such as naloxone and naltrexone.
