The receptor-opsonin complex can also create byproducts like C3b and C4b which are important components of the complement system.
12.
Opsonins are normally soluble proteins, which when bound to the surface of a cell induce phagocytes to phagocytose that cell.
13.
As well as endocytic PRRs, phagocytes also express opsonin receptors such as Fc receptor and complement receptor 1 ( CR1 ).
14.
Over 30 proteins and protein fragments make up the complement system, including globulin fraction of blood serum and can serve as opsonins.
15.
He developed a system of anti-typhoid fever inoculation and a method of measuring protective substances ( opsonin ) in human blood.
16.
The co-stimulation of endocytic PRR and opsonin receptor increases the efficacy of the phagocytic process, enhancing the lysosomal elimination of the infective agent.
17.
By itself, IgM is an ineffective opsonin; however it contributes greatly to opsonization by activating complement and causing C3b to bind to the antigen.
18.
Exposure of these Gram-negative bacteria to SAA1 promotes uptake of the bacteria by neutrophils, suggesting that SAA1 serves as an opsonin that enhances bacteria clearance.
19.
As well as endocytic PRRs, phagocytes also express opsonin receptors Fc receptor and complement receptor 1 ( CR1 ), which bind to antibodies and C3b, respectively.
20.
It is thought to assist in opsonin-mediated phagocytosis ), which express a receptor for CRP . It plays a role in innate immunity as an early defense system against infections.
