As for oral toxicity, when the fungicide is transferred via food into the body, it must be metabolized before it can do any damage.
12.
The mixture of " Tridax procumbens " and " A . sativum " extracts was better at controlling Leishmania mexicana infection while not being toxic when tested in the acute oral toxicity assay in mice.
13.
They are toxic if massive doses are ingested ( acute oral toxicity of 2 g per kg of body weight of pure putrescine in rats, a larger dose for cadaverine ); there are no effects at all for a tenth of that dose.
14.
Because of its low chronic oral toxicity, propylene glycol was classified by the U . S . Food and Drug Administration as " generally recognized as safe " ( GRAS ) for use as a direct food additive, including frozen foods such as ice cream and frozen desserts.
15.
The Human and Environmental Risk Assessment ( HERA ) project performed a thorough investigation of all alkyl sulfates, as such the results they found apply directly to ALS . Most alkyl sulfates exhibit low acute oral toxicity, no toxicity through exposure to the skin, concentration dependent skin irritation, and concentration dependent eye-irritation.
16.
In Acute Oral Toxicity Study, no mortality was found at the end of study and sign of toxicity like change in skin and fur, eyes and mucous membrane, and also respiratory, circulatory, autonomic, and central nervous system and somatomotor activity, behavior pattern, sign of tremors, convulsions, salvation, lethargy, sleep, coma were also not found.
17.
Further data from Eastman's internal studies was released after the Elk River, West Virginia ( 2014 ) spill, including the studies upon which the LD-50 estimate was based and one 28-day study of oral toxicity of pure MCHM which concluded that 400 mg / kg doses were associated with erythropoietic, liver, and kidney effects, though these were not considered more than " minor toxicity " and the " no observed effect " level was considered to be 100 mg / kg / day . [ 43]