The electron-withdrawing group ( EWG ) alpha to the phosphonate is necessary for the final elimination to occur.
12.
In contrast to phosphonium ylides used in the Wittig reaction, phosphonate-stabilized carbanions are more nucleophilic but less basic.
13.
The systematic name of this enzyme class is "'ATP phosphohydrolase ( phosphonate-transporting ) " '.
14.
Alternatively, under certain conditions the dialkyl phosphonate ( dialkyl phosphite ) may be isolated, as well as some alkyl chloride:
15.
Furthermore, they serve as carriers for radionuclides in bone cancer treatments ( see samarium-153-ethylene diamine tetramethylene phosphonate ).
16.
The naturally occurring phosphonate 2-aminoethylphosphonic acid was first identified in 1959 in plants and many animals, where it is localized in membranes.
17.
Bisphosphonate-based drugs'specificity comes from the two phosphonate groups ( and possibly a hydroxyl at ) that work together to coordinate calcium ions.
18.
Replacing the carboxylate group at the C1 to phosphonate group led the drug to be more potent with high affinity to form ionic interaction with the active site.
19.
A promising treatment for preventing infection of individual oak and tanoak trees not for curing an already established infection is a phosphonate fungicide marketed under the trade name Agri-fos.
20.
Some " Cyanothece " species also are capable of tryptophan degradation, methionine salvage, conversion of stored lipids into carbohydrates, alkane and higher alcohol synthesis, and phosphonate metabolism.
