| 11. | It is also dependent on several microtubule-associated proteins such as adenomatous polyposis coli ( APC ).
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| 12. | Familial adenomatous polyposis ( FAP ) is caused by an inherited, inactivating mutation in the APC gene.
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| 13. | The most common mutation in familial adenomatous polyposis is a deletion of five bases in the APC gene.
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| 14. | This approach was used in 2012 in clinical trials to try to treat patients with Familial Adenomatous Polyposis.
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| 15. | Is a Japanese geneticist best known for identifying the tumor suppressor gene APC responsible for Familial Adenomatous Polyposis.
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| 16. | In familial adenomatous polyposis, the abnormality is a mutation in the APC gene, resulting in its inactivity.
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| 17. | Related polyposis conditions are familial adenomatous polyposis, attenuated familial adenomatous polyposis, Birt Hogg Dub?syndrome and MUTYH.
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| 18. | Related polyposis conditions are familial adenomatous polyposis, attenuated familial adenomatous polyposis, Birt Hogg Dub?syndrome and MUTYH.
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| 19. | Related polyposis conditions are familial adenomatous polyposis, attenuated familial adenomatous polyposis, Birt Hogg Dub?syndrome and MUTYH.
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| 20. | Like the adenomatous polyposis mutation, the new mutation was also producing truncated APC proteins but by a novel mechanism.
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