| 11. | Bub1, Rae1 has more promiscuous binding as it binds both the nuclear pore complex and Bub1.
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| 12. | The entry and exit of large molecules from the nucleus is tightly controlled by the nuclear pore complexes.
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| 13. | If the cell is synthesizing DNA each pore complex needs to transport about 100 histone molecules per minute.
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| 14. | Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex.
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| 15. | Aladin is a component of the nuclear pore complex, to which it is attached by nucleoporin NDC1.
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| 16. | He has also proposed an analytical model to elucidate the mechanism of protein transport across the nuclear pore complex.
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| 17. | This is because it interacts with both RNA-binding adapter proteins and components of the nuclear pore complex.
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| 18. | Small particles ( < ~ 40 kDa ) are able to pass through the nuclear pore complex by passive diffusion.
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| 19. | This is followed by an energy-dependent translocation of the nuclear protein through the channel of the pore complex.
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| 20. | FG-nucleoporins also contain a globular portion that serves as an anchor for attachment to the nuclear pore complex.
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