During this time he published research on vibration sense, patent ductus arteriosus, paroxysmal nodal tachycardia, and primordial germ cells.
12.
During foetal development gonocytes develop from primordial germ cells and following this SSCs develop from gonocytes in the testis.
13.
Alkaline phosphatase is elevated in undifferentiated pluripotent stem cells, and the primordial germ cells which produce spermatozoa and oocytes.
14.
Specialized primordial germ cells are forming and migrating from the yolk sac to the embryonic gonads during week eight and nine.
15.
Oogenesis takes place during fetal life, in which primordial germ cells undergo mitosis until a few weeks prior to birth, forming oogonia.
16.
Expression of " egfl7 " has also been reported in primordial germ cells and in adult ovaries and testes and in neurons.
17.
During spermatogenesis, DNA methylation marks are erased in the primordial germ cells and re-established during the production of sperm through genetic imprinting.
18.
The genetic lineage-tracing experiments indicate that the Blimp1-positive cells originating from the proximal posterior epiblast cells are indeed the lineage-restricted primordial germ cell precursors.
19.
During the 6th to 8th week of female ( XX ) embryonic development, the primordial germ cells grow and begin to differentiate into oogonia.
20.
For example, in mouse primordial germ cells, a genome wide de-methylation even occurs; by implantation stage, methylation levels return to their prior somatic levels.