Pinazepam differs from other benzodiazepines in that it has a propargyl group at the " N "-1 position of the benzodiazepine structure.
12.
The intermediate complex can be captured with many electrophiles such as propargyl bromide ( pictured, forming the allene ), benzoyl chloride and allyl bromide.
13.
Optically active tryptophan which adheres to the regioselectivity of the Larock indole synthesis can also be synthesized using o-iodoaniline with propargyl substituted bislactim ethyl ether.
14.
For example, aqueous abiotic hydrolysis degrades organophosphates, carboxylic acid esters, carbamates, carbonates, some halides ( methyl bromide, propargyl ) and many more.
15.
"' Asymmetric addition of alkynylzinc compounds to aldehydes "'is an enantioselective chemical reaction where alkynylzinc reagents react with aldehydes to generate propargyl alcohols.
16.
Using a Rh 2 ( OAc ) 4 catalyst in benzene, diazodione underwent a 1, 3-dipolar cycloaddition reaction with methyl propiolate and methyl propargyl ether.
17.
Propargyl alcohols are versatile precursors to various complex molecules making the asymmetric addition of alkynylzinc compounds to aldehydes a particularly useful method for the synthesis of natural products and pharmaceutical drugs.
18.
The significance of this variation is in the fact that it increases the scope of the Paal Knorr by taking advantage of the wealth of acetylene chemistry that exists, specifically that for the generation of propargyl alcohols.
19.
It is proposed that intramolecular cyclopropanation occurs via a 1, 2 shift of the propargyl ester mediated by Au to give a " syn " Au vinyl carbenoid species ( "'29 "').
20.
The reaction with methyl propargyl ether affords one regioisomer resulting from the HOMO dipolarophile-LUMO dipole interaction, which has largest coefficients on the carbon distal to the carbonyl group of the carbonyl ylide and on the methyl propargyl ether terminal alkyne carbon.
