Integrasone inhibits HIV-1 integrase, the viral enzyme responsible for integrating the HIV provirus into the host genome.
12.
Endogenous retroviruses and other EVEs that occur as proviruses can potentially remain capable of producing infectious virus in their endogenous state.
13.
Integration is a point of no return for the cell, which becomes a permanent carrier of the viral genome ( provirus ).
14.
High levels of MMTV are expressed in lymphoid leukemias of mouse strain GR and DBA / 2 which contain extra integrated MMTV proviruses.
15.
The virus RNA genome is reverse transcribed by reverse transcriptase into DNA . This DNA intermediate state of the virus is called the provirus.
16.
The theory is to create a provirus with a deletion in the pathogenic gene that confers oncogenesis ( " tax ) ".
17.
A provirus is a viral DNA that has been incorporated into the chromosome of a host cell, often by retroviruses such as HIV.
18.
The provirus is a specialized form of eukaryotic retrotransposon, which can produce RNA intermediates that may leave the host cell and infect other cells.
19.
Do any provirus have specific loci at which the insert their genomes ?-- talk ) 12 : 55, 15 March 2006 ( UTC)
20.
P21 mediates the resistance of hematopoietic cells to an infection with HIV by complexing with the HIV integrase and thereby aborting chromosomal integration of the provirus.
