MDR1, MRP2, MRP4 and URAT1 then transports these organic anions from the cytoplasm of the S2 cells into the lumen of the proximal convoluted tubules.
12.
Researchers at MIT claim to have designed a bioartificial device that replicates the function of the nephron s glomerulus, proximal convoluted tubule and loop of Henle.
13.
The proximal convoluted tubule of the kidney, the liver, the pancreas, and the intestine are sources of GGT, in decreasing order of tissue concentration.
14.
Finally, would I be correct in saying that PTH increases phosphate excretion through the inhibition of Brush border membrane sodium dependent phosphate transporters in the proximal convoluted tubule?
15.
Sodium and glucose are co-transported by the SGLT-2 protein into the tubular epithelial cells across the brush-border membrane of the proximal convoluted tubule.
16.
They are located on proximal convoluted tubules, and their activation suppresses the activity of sodium-hydrogen antiporter and Na + / K +-ATPase, preventing reabsorption of sodium.
17.
The ultrafiltrate is passed through, in turn, the proximal convoluted tubule, the loop of Henle, the distal convoluted tubule, and a series of collecting ducts to form urine.
18.
In short, under normal conditions, the net effect of carbonic anhydrase in the urinary lumen and cells of the proximal convoluted tubule is to acidify the urine and transport bicarbonate ( ) into the body.
19.
Fluid in the filtrate entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries, including approximately two-thirds of the filtered salt and water and all filtered organic solutes ( primarily glucose and amino acids ).
20.
It begins in the cortex, receiving filtrate from the proximal convoluted tubule, extends into the medulla as the descending limb, and then returns to the cortex as the ascending limb to empty into the distal convoluted tubule.