Propargylglycine and ?-cyanoalanine are two sterically hinders the active site, blocking cysteine from attacking pyridoxal phosphate.
12.
This intermediate ( 5-HTP ) is decarboxylated by pyridoxal phosphate and 5-hydroxytryptophan decarboxylase to produce serotonin.
13.
This homodimeric enzyme is a pyridoxal phosphate ( PLP )-dependent decarboxylase and is highly specific for its histidine substrate.
14.
The enzyme alliinase, which contains pyridoxal phosphate ( PLP ), cleaves alliin, generating allysulfenic acid, pyruvate, and ammonium.
15.
The ? subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate ( PLP ) dependent reaction.
16.
Cystathionase uses pyridoxal phosphate to facilitate the cleavage of the sulfur-gamma carbon bond of cystathionine, resulting in the release of cysteine.
17.
"' Dunathan stereoelectronic hypothesis "'is a concept in chemistry to explain the stereospecefic cleavage of bonds using pyridoxal phosphate.
18.
A decarboxylase with cofactor pyridoxal phosphate ( PLP ) removes CO 2 from 5-hydroxy-L-tryptophan to produce 5-hydroxytryptamine.
19.
Lys-680 is involved in binding the pyridoxal phosphate, which is the active form of vitamin B 6, a cofactor required by myophosphorylase.
20.
Some enzymes utilize non-amino acid cofactors such as pyridoxal phosphate ( PLP ) or thiamine pyrophosphate ( TPP ) to form covalent intermediates with reactant molecules.