| 11. | Low-level quinolone resistance has been linked to changes in cell permeability and efflux pumps.
|
| 12. | Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
|
| 13. | Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp . in Spain.
|
| 14. | Ozenoxacin is active against some bacteria that have developed resistance to currently used quinolone and fluoroquinolone antibiotics.
|
| 15. | The first quinolone was nalidixic acid-introduced in 1962 for treatment of urinary tract infections in humans.
|
| 16. | It may be used to treat Legionnaire's disease as a substitute for a macrolide or quinolone.
|
| 17. | "' Oxolinic acid "'is a quinolone antibiotic developed in Japan in the 1970s.
|
| 18. | Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.
|
| 19. | Quinolone antibiotics may bind to metallic cations such as bismuth, and should not be taken concurrently with bismuth subsalicylate.
|
| 20. | It also has activity against " Neisseria gonorrhoeae " including strains that are resistant to other quinolone antibiotics.
|