| 11. | They are involved in primosome function both at arrested replication forks and at the chromosomal origin.
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| 12. | Repair of interstrand DNA crosslinks is triggered when the DNA replication fork is unable to continue.
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| 13. | If replication forks move freely in chromosomes, catenation of nuclei is aggravated and impedes mitotic segregation.
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| 14. | Alternatively, the invading 3 end near Chi can prime DNA synthesis and form a replication fork.
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| 15. | During lagging strand synthesis, the replicative polymerase sends the lagging strand back toward the replication fork.
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| 16. | PCNA fully encircles the DNA template strand and must be loaded onto DNA at the replication fork.
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| 17. | Histones are reassembled onto newly replicated DNA after the replication fork by CAF-1 and Rtt106.
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| 18. | There are also proteins involved in reassembling histones behind the replication fork to reestablish the nucleosome conformation.
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| 19. | They also function in other DNA damage response repair processes including recovering and stabilizing stalled replication forks.
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| 20. | Leading strand synthesis then proceeds continuously, while the DNA is concurrently unwound at the replication fork.
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