| 11. | This is a convenient route to secondary amines of the form RCH 2 NH R2.
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| 12. | Nitroaromatics can also give this reaction, reducing nitro to amine and imine giving secondary amines.
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| 13. | For some applications, the primary and secondary amines are often subjected to the Leuckart reaction.
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| 14. | Reflecting the hydrophilic character of the secondary amine and hydroxyl groups, DEA is soluble in water.
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| 15. | The nitrilium ions thus formed can then be reduced to secondary amines with sodium borohydride in diglyme.
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| 16. | By the end of this step a secondary amine, the base of the drug, is formed.
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| 17. | In the same year JP Devlin and colleagues discovered the bicyclic secondary amine structure of anatoxin-a.
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| 18. | In the Mannich reaction, primary or secondary amines or ammonia, are employed for the activation of formaldehyde.
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| 19. | Metabolism of other 1-methylated-ergoloids to their secondary amine derivatives has been frequently noted in mammals.
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| 20. | Different acid-stability of the benzhydrylic protective groups allows the selective removal from secondary amines for subsequent branching.
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