On the rare occasions when consequential mutations are beneficial, they are quickly favored by natural selection and outnumber the silent mutations.
12.
This can result in lower expression of a particular gene containing that silent mutation if the mutation occurs within an exon.
13.
Transfer RNA ( tRNA ) availability is one of the reasons that silent mutations might not be as silent as conventionally believed.
14.
Nucleotide mutations that do change the specified amino acid are usually harmful; hence these consequential mutations are less common than the silent mutations.
15.
LPS has an additional CTC to CTG silent mutation, while HPS does not and shares the CTC sequence at this location with APS
16.
In particular, silent mutations are not point accepted mutations, nor are mutations which are lethal or which are rejected by natural selection in other ways.
17.
Among three specimens of " O . couesi ", the sequence in this segment differed by only 1 %, and all changes were silent mutations.
18.
Silent mutations are base substitutions that result in no change of the amino acid or amino acid functionality when the altered messenger RNA ( mRNA ) is translated.
19.
In molecular cloning experiments, it can be useful to introduce silent mutations into a gene of interest in order to create or remove recognition sites for restriction enzymes.
20.
For example, silent mutations that do not change the corresponding amino acid sequence of a gene may change the frequency of guanine-cytosine base pairs ( GC content ).
