In secondary spontaneous pneumothorax, the estimated annual AAIR is 6.3 and 2.0 cases per 100, 000 person-years for males and females, respectively, with the risk of recurrence depending on the presence and severity of any underlying lung disease.
12.
The first case of spontaneous pneumothorax associated with BHD was discovered in 1986; the first case of renal cancer followed in 1993 and the presence of lung cysts in people with BHD was confirmed in 1999 . It was formerly thought that people with Birt Hogg Dub?syndrome were at higher risk for colorectal polyps and neoplasms, but this has been disproven.
