Staurosporine, a nonspecific protein kinase C inhibitor can induce squamous metaplasia in breast tissue while other known PKC inhibitors did not show this effect . cAMP stimulation can also induce squamous metaplasia.
12.
Typical usage in North America is a synonym of nonpuerperal mastitis, including the special cases of granulomatous mastitis, comedo mastitis, subareolar abscess with or without squamous metaplasia of lactiferous ducts and fistulation.
13.
Staurosporine, a nonspecific protein kinase C inhibitor can induce squamous metaplasia in breast tissue while other known PKC inhibitors did not show this effect . cAMP stimulation can also induce squamous metaplasia.
14.
Loricrin is expressed in the granular layer of all keratinized epithelial cells of mammals tested including oral, esophageal and stomach mucosa of rodents, tracheal squamous metaplasia of vitamin A deficient hamster and estrogen induced squamous vaginal epithelium of rats.
15.
Women in the younger group mostly have inverted nipples due to squamous metaplasia that lines the ducts more extensively compared to other women and produces keratin plugs which in turn lead to duct obstruction and then duct dilation, secretory stasis, inflammation, infection and abscess.
16.
Other changes include impaired immunity ( increased risk of ear infections, urinary tract infections, Meningococcal disease ), hyperkeratosis ( white lumps at hair follicles ), keratosis pilaris and squamous metaplasia of the epithelium lining the upper respiratory passages and urinary bladder to a keratinized epithelium.
17.
The U . S . Public Health Service commented on this study saying that due to the present squamous metaplasia in the respiratory tracts of the rats that " This study should not be used to calculate the safe inhalation dose of paraquat in humans ."
