There are no vaccines to prevent these infections so drugs such as pentamidine and suramin, benznidazole and nifurtimox and used to treat infections.
12.
Suramin, approved for African Sleeping Sickness-induced blindness, and once studied for cancer and HIV, may reverse early renal failure.
13.
Specifically, renal function after suramin treatment was similar to non-pathological controls : they had less proteinuria, inflammation, and fibrosis.
14.
Such drugs already exist, and one _ called suramin _ is already being tested as a treatment for prostate cancer, the scientists said.
15.
Suramin is also known to inhibit eukaryotic DNA primase by competing with GTP, so suramin is likely to inhibit DnaG via a similar mechanism.
16.
Suramin is also known to inhibit eukaryotic DNA primase by competing with GTP, so suramin is likely to inhibit DnaG via a similar mechanism.
17.
After hearing that Post's spinal fluid was clean, the doctor on call recommended suramin, another toxic remedy, used since the 1920s.
18.
When tumors appeared in her liver, she turned again to clinical trials, becoming the first patient in a study that combined the drugs taxol and suramin.
19.
Suramin has been applied clinically to HIV / AIDS patients resulting in a significant number of fatal occurrences and as a result the application of this molecule was abandoned for this condition.
20.
Further consistent with this structural hypothesis is the knowledge that suramin-a polysulfated drug ( with substantial corresponding negative charge ) has been found to inhibit sperm-zona pellucida binding.