Use of triple tissue blastocyst reconstitution to study the development of diploid parthenogenetic primitive ectoderm in combination with fertilization-derived trophectoderm and primitive endoderm . " Genet.
12.
In mammals ( except monotremes ), the ICM will ultimately form the " embryo proper ", while the trophectoderm will form the placenta and extra-embryonic tissues.
13.
In normal development, the appearance of an outer sheath, the trophectoderm, is the first sign that a fertilized egg has developed into more than one type of cell.
14.
Mouse embryos that are Oct-4-deficient or have low expression levels of Oct-4 fail to form the inner cell mass, lose pluripotency and differentiate into trophectoderm.
15.
Furthermore, these cells pump fluid into the interior of the blastocyst, causing the formation of a polarized blastocyst with the ICM attached to the trophectoderm at one end ( see figure ).
16.
Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation.
17.
Although it was originally hypothesized to be essential for specification of trophectoderm lineage, it was later shown that functional trophectoderm can be produced leading to formation of blastocysts under in vitro conditions that suppress oxidative stress.
18.
Although it was originally hypothesized to be essential for specification of trophectoderm lineage, it was later shown that functional trophectoderm can be produced leading to formation of blastocysts under in vitro conditions that suppress oxidative stress.
19.
His studies related to differential transcriptional regulation of interferon-t by ETS-2 and Oct-4 transcription factors, led to the identification of a putative developmental switch that may lead to the formation of trophectoderm in early embryo development.
20.
Before implanting the DNA from a skin cell into an egg, scientists would turn off a gene that helps direct the formation of the trophectoderm, an outer layer of cells that is crucial in the first stages of development and which eventually forms the placenta.
