In 1931, William B . Castle and his assistant Cornelius P . Rhoads studied hookworm and tropical sprue in relation to anemia.
12.
Chronic diseases of malabsorption may affect the small intestine, including the autoimmune coeliac disease, infective Tropical sprue, and congenital or surgical short bowel syndrome.
13.
Anemia was widespread on the island because of the endemic parasite hookworm and tropical sprue, the latter a disease which scientists thought possibly related to diet.
14.
The work of the Institute expanded as the scientists investigated diseases such as malaria, dengue fever, filariasis, hookworm, many unidentified fevers, amoebic dysentery, tropical sprue, leprosy, yaws and gangosa.
15.
That day he had fallen seriously ill at sea with tropical sprue, an infection sometimes aggravated by poor nutrition which interferes with the small intestine's ability to absorb nutrients, resulting in symptoms related to malnutrition.
16.
There is an overlap in findings between tropical sprue, post-infectious irritable bowel syndrome and small intestinal bacterial overgrowth in the pathophysiology of the three conditions and also SIBO can similarly sometimes be triggered by an acute gastrointestinal infection.
17.
The use of folic acid and vitamin B 12 in the treatment of tropical sprue was promoted in the late 1940s by Dr . Tom Spies of the University of Alabama, while conducting his research in Cuba and Puerto Rico.
18.
The institute had a long relationship with the government of Puerto Rico, conducting research and working on health issues there, such as anemia ( caused by hookworm and tropical sprue ), as well as polio and a variety of diseases.
19.
In the late 1940s, Dr . Spies experimented with the use of folic acid and other vitamins in the treatment of tropical sprue, which was a deadly disease at that time; he conducted his research in Cuba and Puerto Rico.
20.
Coeliac disease ( also known as " coeliac sprue or gluten sensitive enteropathy " ), has similar symptoms to tropical sprue, with the flattening of the villi and small intestine inflammation and is caused by an autoimmune disorder in genetically susceptible individuals triggered by ingested gluten.
