These individuals may present with a unique set of physical characteristics such as xanthelasmas ( yellow deposits of fat underneath the skin often presenting in the nasal portion of the eye ), tendon and tuberous xanthomas, arcus juvenilis ( the graying of the eye often characterized in older individuals ), arterial bruits, claudication, and of course atherosclerosis.
12.
In January 2010, Dr Vito Franco, professor of Palermo University, published research in an article in " La Stampa " newspaper and at a medical conference in Florence which suggested that the subject showed clear signs of xanthelasma, small accumulations of cholesterol-rich material under the skin, perhaps caused by problems in her biliary tract, due to hyperlipidemia, an inherited metabolic disorder.
