| 11. | Acrosin digests the zona pellucida and membrane of the oocyte.
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| 12. | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo.
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| 13. | It is here that lysis of the zona pellucida occurs.
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| 14. | The zona pellucida is a thick membrane that surrounds the unfertilised eggs of mammals.
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| 15. | After reaching the zona pellucida the actual acrosome reaction begins.
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| 16. | This cross-linking contributes to the hardening of the zona pellucida.
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| 17. | Enzymes on the inner acrosomal membrane digest the zona pellucida.
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| 18. | The zona pellucida is a glycoprotein membrane surrounding the plasma membrane of an ovum.
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| 19. | Currently, zona drilling using a laser is the predominant method of opening the zona pellucida.
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| 20. | Finally, while there has been ovarian pathogenesis found in some trials using zona pellucida vaccines,
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