Loss of DAX1 function leads to adrenal insufficiency and hypogonadotropic hypogonadism, which are the main characteristics of this disorder.
22.
In addition, concurrent use of etomidate with opioids and / or benzodiazepines, is hypothesized to exacerbate etomidate-related adrenal insufficiency.
23.
Other hormonal problems occurring in at least a quarter of patients include type 2 diabetes, hypothyroidism and adrenal insufficiency.
24.
There is an additional elevated risk of Adrenal gland bleeds leading to Waterhouse Friderichsen syndrome ( Primary Adrenal Insufficiency ).
25.
The ACTH stimulation test does not distinguish between primary adrenal insufficiency and secondary insufficiency or adrenocortical destruction caused by mitotane overdose.
26.
Addison's disease, which describes adrenal insufficiency, is named after a British physician, Dr . Thomas Addison, who described it in 1855.
27.
Causes of adrenal insufficiency can be categorized by the mechanism through which they cause the adrenal glands to produce insufficient cortisol.
28.
During his years of practice, Barnes also began to believe that virtually all his hypothyroid patients had concomitant undiagnosed adrenal insufficiency.
29.
If the short test is abnormal, the long test is used to differentiate between primary adrenal insufficiency and secondary adrenocortical insufficiency.
30.
This is called secondary or tertiary adrenal insufficiency and is caused by lack of production of CRH in the hypothalamus, respectively.
