The mechanism of ring closure is complex, but involves an aldol condensation at C-2 and C-7.
22.
The last step is an elimination ( Aldol condensation ) reaction with an E 1 " CB " mechanism.
23.
Next, this intermediate undergoes an aldol condensation to form the proposed bicyclic intermediate ( "'5 "').
24.
The data from Taura s study of OLS's enzyme kinetics show that OLS catalyzes a decarboxylative-aldol condensation to produce olivetol.
25.
The C-H groups adjacent to the carbonyl in thioesters are mildly acidic ( more so than in esters ) and undergo aldol condensations.
26.
The aldol condensation is an intramolecular process that creates the namesake ring of the Robinson annulation product going from step C through to step F.
27.
The high proportion of byproducts and low yield are explained by the easily reversible nature of the aldol condensation, and carbonyl chemistry in general.
28.
2-Propyl-2-heptenal is obtained from pentanal by aldol condensation, which is di-2-propylheptyl phthalate ( DPHP ).
29.
You may also want to protect your aldehyde once it is made; else you may end up with unwanted side reactions like the Aldol condensation.
30.
Zinc enolates, prepared from alkali metal enolates and ZnCl 2, provide control of stereochemistry in aldol condensation reactions due to chelation on to the zinc.
