On the opposite side of the each subunit from each active site is the allosteric site, at the interface between subunits in the dimer.
22.
In non-competitive inhibition, the inhibitor binds to an allosteric site, which alters the active site and makes it inaccessible to the substrate.
23.
In mixed inhibition, the inhibitor binds to an allosteric site, i . e . a site different from the active site where the substrate binds.
24.
It is an allosteric site-binding inhibitor with a primary target of IKK-2 and blocks the NF-?B-dependent transcription in mice.
25.
Proteins contain allosteric sites which, when bound to by small molecules, can alter a protein's conformation and ultimately affect the protein's activity.
26.
The glycogen phosphorylase dimer has many regions of biological significance, including catalytic sites, glycogen binding sites, allosteric sites, and a reversibly phosphorylated serine residue.
27.
In an environment with a low glucose concentration, cAMP accumulates and binds to the allosteric site on CRP ( cAMP receptor protein ), a transcription activator protein.
28.
A non-regulatory allosteric site refers to any non-regulatory component of an enzyme ( or any protein ), that is not itself an amino acid.
29.
This is similar to allosteric sites, but differs in the fact that, in order for an enzyme to be active, its exosite typically must be occupied.
30.
They are defined as ligands able to directly activate a receptor by binding to a receptor site distinct from the primary ( orthosteric ) site, the allosteric site.
