CDNA sequences are available for several aminopeptidases and a crystal structure of the open state of human endoplasmic reticulum Aminopeptidase 1 ERAP1 is presented here.
22.
Using a number of tissue homogenates from " Periplaneta americana " a soluble aminopeptidase as a key enzyme that degrades proctolin was identified.
23.
Polymorphisms in ACE or aminopeptidase P ( APP ), another enzyme responsible for bradykinin degradation ( 20 % ) may also contribute to HTRs.
24.
Aminopeptidase N has the same ability to interact with plant lectins C-type mannose-binding and also serves as a receptor for a retrovirus.
25.
A similar cycle of activity occurs in the posterior midgut and posterior midgut lumen, whereas aminopeptidase in the posterior midgut epithelium decreases in activity during digestion.
26.
These agents increase the level of aminopeptidase P, an enzyme that inactivates kinins; kinins ( especially bradykinin ) are responsible for the manifestations of angioedema.
27.
Depending on whether the amino acid is released from the amino or the carboxy terminal, an exopeptidase is further classified as an aminopeptidase or a carboxypeptidase, respectively.
28.
The GWAS identified, in addition to HLA-A29, the " endoplasmic reticulum aminopeptidase ( ERAP ) 2 " gene strongly associated with birdshot chorioretinopathy.
29.
Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
30.
Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
