| 21. | RACGAP1 also interacts with PRC1 to stabilize and maintain the central spindle as anaphase proceeds.
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| 22. | PRC1 is normally inhibited until anaphase onset by CDK1 mediated phosphorylation, preventing its dimerization.
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| 23. | Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis.
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| 24. | "Anaphase lag " occurs when the movement of one chromatid is impeded during anaphase.
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| 25. | "Anaphase lag " occurs when the movement of one chromatid is impeded during anaphase.
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| 26. | Anaphase starts when the anaphase promoting complex marks an inhibitory chaperone called securin with ubiquitin for destruction.
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| 27. | Anaphase starts when the anaphase promoting complex marks an inhibitory chaperone called securin with ubiquitin for destruction.
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| 28. | This would be accomplished by regulation of the anaphase-promoting complex, securin, and separase.
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| 29. | Figure 4 : Potential network diagram involving securin and separase to generate switch-like activation of anaphase
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| 30. | Overexpression of cyclin A2 in mammalian cells can result in the delayed onset of metaphase and anaphase.
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