| 21. | He has been involved in registration trials of antineoplastic agents in a variety of solid tumors.
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| 22. | The following nitrogen mustard ester of estradiol is an alkylating antineoplastic agent and has been marketed:
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| 23. | "' Carboxycyclophosphamide "'is an inactive metabolite of the cytotoxic antineoplastic drug cyclophosphamide.
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| 24. | The antineoplastic alkylating agent, teroxirone, is formed by reacting cyanuric acid with 3 equivalents of epichlorohydrin.
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| 25. | "' Lurtotecan "'is a semi-synthetic analog of camptothecin with antineoplastic activity.
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| 26. | Chromonychia can be induced by antineoplastic drugs with few distinct forms, the most frequently seen is melanonychia.
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| 27. | "' Exatecan "'is a drug which is an analogue of camptothecin with antineoplastic activity.
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| 28. | In the area of platinum-based antineoplastic agents, spectator ( and nonspectator ) ligands greatly affect efficacy.
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| 29. | "' Estramustine "'( synthetic steroidal estrogen and alkylating antineoplastic agent that was never marketed.
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| 30. | Indeed, staurosporine and its derivatives possess antineoplastic activity in vivo in human tumors grown as xenografts in nude mice.
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