It also has the effect of decreasing the steroid's affinity for sex hormone-binding globulin, a protein that deactivates steroid molecules and prevents them from further reactions with the body.
22.
Estradiol often will chemically bind with a protein called sex hormone-binding globulin, or SHBG . This changes the way in which the hormone can interact with cells, a function called bioavailability.
23.
Another useful dynamic test involves measuring the response to exogenous steroids; individuals with AIS show a decreased response in serum sex hormone binding globulin ( SHBG ) after a short term administration of anabolic steroids.
24.
Also in contrast with EE and especially with E2, E4 does not bind to sex hormone binding globulin ( SHBG ) and does not stimulate the production of SHBG " in vitro ".
25.
In nephrotic syndrome, urinary loss of transferrin, along with other serum proteins such as thyroxine-binding globulin, gammaglobulin, and anti-thrombin III, can manifest as iron-resistant microcytic anemia.
26.
Since salivary hormone tests measure only those hormones that are not bound to sex hormone-binding globulin ( SHBG ) or albumin, they are regarded as reflecting only the bioactive ( free ) fraction.
27.
Furthermore, estrogens can increase blood levels of the protein sex hormone binding globulin ( SHBG ), which binds free testosterone ( the active form ) leading to decreased action of testosterone in male breast tissue.
28.
Men with premature androgenic alopecia tend to have lower than normal values of sex hormone-binding globulin ( SHBG ), follicle stimulating hormone ( FSH ), testosterone, and epitestosterone when compared to normal controls.
29.
Sex hormone-binding globulin levels were mildly elevated ( 6.0 10.0 nmol / L ), while thyroxine-binding globulin, corticosteroid-binding globulin, and prolactin levels were all normal.
30.
Sex hormone-binding globulin levels were mildly elevated ( 6.0 10.0 nmol / L ), while thyroxine-binding globulin, corticosteroid-binding globulin, and prolactin levels were all normal.