| 21. | The situation is worse if drugs such as chloroquine are used which accumulate progressively.
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| 22. | Traditional treatments such as the drug chloroquine are losing effectiveness as the parasite develops resistance.
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| 23. | Barman said mosquitoes appear to have become resistant to the commonly used drug, chloroquine.
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| 24. | Adverse reactions are generally similar in severity and type to that seen in chloroquine treatment.
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| 25. | The first type of resistance to be acknowledged was to chloroquine in Thailand in 1957.
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| 26. | It is related to chloroquine and mefloquine.
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| 27. | This MDA comprised 300 mg chloroquine base and 45 mg pyrimethamine weekly for nine weeks.
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| 28. | It was then decided to mix the remaining stock of pyrimethaminized salt with chloroquine powder.
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| 29. | A fresh batch of chloroquine tablets was sent to treat 200 patients still suffering from malaria.
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| 30. | Chloroquine, the cheapest and safest malaria drug is rapidly losing its effectiveness, he said.
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