Because mutations in the gene are extremely rare, most cases result from consanguineous matings, for example, between cousins.
22.
The observed endogamy is primarily consanguineous marriages, where the bride and the groom share a biological grandparent or other near ancestor.
23.
Consanguineous endogamous marriages are most common for women in Muslim communities in the Middle East, North Africa and Islamic Central Asia.
24.
A mutation that causes loss of Na v 1.7 function has been detected in three consanguineous families from northern Pakistan.
25.
GM2A mutations are rarely reported, and the cases that are observed often occur with consanguineous parents or in genetically isolated populations.
26.
Shi'ite Islam goes further in this restriction by also prohibiting marriage to the consanguineous kin of a milk-parent.
27.
The practice of endogamous consanguineous marriage dramatically limits the marriagable pool; it inherently encourages marriages arranged according to tradition and birth.
28.
This disorder was discovered in two unrelated Israeli boys 3 and 5 years of age, each the offspring of consanguineous parents.
29.
Generations of consanguineous marriages are believed to have led to this outsized population of people who cannot hear, the people believe.
30.
Younger ages of marriage are commonly seen in consanguineous marriages, which may account for the increase in fertility seen in these unions.
