Experimentally found within mouse cortical granules, N-Acetylglucosaminidase is a glycosidase that hydrolyzes N-acetylglucosamine residues located on the zona pellucida.
22.
In mammals, the first calcium wave occurs within 1 4 minutes following fertilization, and cortical granule exocytosis occurs within 5 30 minutes following fertilization.
23.
Peptidylarginine deiminiase is a secretory protein within the cortical granule that contributes to regulation of the embryo's development prior to the event of implantation.
24.
To create this barrier cortical granules, specialized exocytose is the release of calcium ions from cortical smooth endoplasmic reticulum in response to sperm binding to the egg.
25.
For example, in the fertilized sea urchin egg, it has been shown that the cortical granule exocytosis immediately follows the calcium increase after approximately 6 seconds.
26.
It can be distinguished from its congeners by its thin body, an absence of cortical granules, and a low number of ciliary rows and adoral polykinetids.
27.
Cortical granules inside the secondary oocyte fuse with the plasma membrane of the cell, causing enzymes inside these granules to be expelled by exocytosis to the zona pellucida.
28.
Despite this association with the cortical reaction, however, evidence has yet to be found supporting that the tissue-type plasminogen activator is a cortical granule component.
29.
In the cortical reaction, cortical granules directly beneath the plasma membrane are released into the space between the plasma membrane and the vitelline membrane ( the perivitelline space ).
30.
Upon release from the cortical granule, p32 appears to either function briefly or undergo a modification shortly after fertilization because only small amounts of p32 are present on the embryo.
