| 21. | Urine odor in cystinuria has a smell of rotten eggs due to the increase in cystine.
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| 22. | But if there is a defect in the carrier protein, cystine is accumulated in lysosomes.
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| 23. | Omega, delta and kappa families of conotoxins have a knottin or inhibitor cystine knot scaffold.
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| 24. | These also selectively reduce the cystine bonds, but are much weaker and work more slowly.
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| 25. | This causes an arginine to cystine substitution at amino acid position 83, a conserved location.
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| 26. | The growth factor cystine knot ( GFCK ) was first observed in the structure of Nature.
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| 27. | Medicinally, it may be used to control kidney stones derived from either uric acid or cystine.
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| 28. | However, it is the combination of methionine and cystine which is considered for completeness of a protein.
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| 29. | The notch extracellular domain is composed primarily of small cystine-rich motifs called EGF-like repeats.
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| 30. | Although tissue damage might depend on cystine accumulation, the mechanisms of tissue damage are not fully understood.
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