Pore-formation is the only known shared function in RTX cytotoxins, and pores are typically cation-selective allowing for an influx of Ca 2 + in target cells.
22.
Tumor necrosis factor ( TNF ) ( also known as TNF-alpha or cachectin ) is a cytotoxin which is derived from a form of white blood cell called monocytes.
23.
The diarrhetic syndromes observed in patients are thought to stem from the three toxins : hemolysin BL ( Hbl ), nonhemolytic enterotoxin ( Nhe ) and cytotoxin K ( CytK ).
24.
When " Climacostomum " is threatened by a predator, such as the ciliate " Dileptus margaritifer, " these cortical cysts release a defensive cytotoxin called Climacostol.
25.
Some microorganisms & ndash; for example, bacteria of the genus " Shigella " & ndash; secrete substances known as cytotoxins, which kill and damage intestinal tissue on contact.
26.
Mo finds Alvy dead of a cytotoxin and evidence that the robot is an experimental combat model capable of self-repair; Alvy's notes also indicate a defect, a weakness to humidity.
27.
Moreover, with the rising popularity of antibody-drug conjugate therapies, toxicity liabilities may be mitigated through targeted delivery of this potent cytotoxin, potentially enabling efficient therapies that use minimal quantities of this complex material.
28.
These proteins can potentially be a mix of neurotoxins ( which attack the nervous system ), hemotoxins ( which attack the circulatory system ), cytotoxins, bungarotoxins and many other toxins that affect the body in different ways.
29.
The resistance to chemotherapy seems to be reversible by administering chemo-resensitization drugs, such as verapamil, which acts not via MK alteration, but by inhibiting the P-glycoprotein pump that exports cytotoxins out of cells.
30.
After tuberculosis and leprosy, Buruli ulcer is the third most common mycobacteriosis of humans . " M . ulcerans " grows optimally on routine mycobacteriologic media at 33 �C and elaborates a necrotizing immunosuppressive cytotoxin ( mycolactone ).
