| 21. | Sulpiride, along with clozapine, has been found to activate DNA demethylation in the brain.
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| 22. | Current antipsychotic drugs, like clozapine and sulpiride, have been shown to also induce demethylation.
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| 23. | Maeder et al . has constructed a ZF-TET1 protein for use in DNA demethylation.
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| 24. | After N-demethylation of oxymorphone, noroxymorphone is further glucuronidated to noroxymorphone-3-glucuronide.
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| 25. | Histones H3 and H4 can also be manipulated through demethylation using histone lysine demethylase ( KDM ).
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| 26. | The demethylation occurs when JmjC utilizes multiple cofactors to hydroxylate the methyl group, thereby removing it.
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| 27. | Further processing of aristolactam I by O-demethylation results in aristolactam Ia, the primary metabolite.
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| 28. | Codeine is metabolised by O-and N-demethylation in the liver to morphine and norcodeine.
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| 29. | The demethylation of sarcosine catalyzed by sarcosine dehydrogenase can proceed with or without the presence of tetrahydrofolate.
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| 30. | They prevent the demethylation of the H3K4 histone protein and open up that part of the chromatin.
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