The amount of opiates can be high provided that the end product is not overly diluted during production, but the amount of diacetylmorphine and 6-monoacetylmorphine created depends on the skills of people making it and the time and conditions of acetylation.
22.
It is described as being virtually identical to heroin and morphine in its effects, and consequently was itself banned internationally in 1930 by the Health Committee of the League of Nations, in order to prevent its sale as an unscheduled alternative to diacetylmorphine.
23.
It is also a precursor for many drugs including heroin ( 3, 6-diacetylmorphine ), hydromorphone ( dihydromorphinone ), and oxymorphone ( 14-hydroxydihydromorphinone ); many morphine derivatives can also be manufactured using thebaine or codeine as a starting material.
24.
In the meantime, the first designer drugs, viz . 3, 6 diesters and 6 monoesters of morphine and acetylated analogues of closely related drugs like hydromorphone and dihydromorphine, were produced in massive quantities to fill the worldwide demand for diacetylmorphine this continued until 1930 when the Committee banned diacetylmorphine analogues with no therapeutic advantage over drugs already in use, the first major legislation of this type.
25.
The production of black tar heroin results in significant amounts of 6-MAM in the final product . 6-MAM is approximately 30 percent more active than diacetylmorphine itself, This is why despite lower heroin content, black tar heroin may be more potent than some other forms of heroin . 6-MAM can be synthesized from morphine using glacial acetic acid with an organic base as a catalyst.
26.
Black tar can contain a variable percentage of heroin, but despite the name, what makes black tar specific as a type is " not " actually its heroin ( " diacetylmorphine " ) content, but rather the greater mixture of lesser acetylated morphine derivatives predominantly 6-MAM ( " 6-monoacetylmorphine " ) and 3-MAM ( " 3-monoacetylmorphine " ).
